A tool utilizing maternal age and potentially other factors like nuchal translucency measurements from ultrasound, blood serum markers, and family history, estimates the statistical likelihood of a pregnancy resulting in a live birth with trisomy 21. For example, such a tool might integrate data from first-trimester screening tests to provide a more individualized assessment.
Providing prospective parents with personalized probability assessments aids informed decision-making regarding further diagnostic testing options like chorionic villus sampling or amniocentesis. These tools offer valuable information before such procedures, which carry inherent risks. Historically, maternal age was the sole consideration, but advancements now incorporate multiple variables for a more precise evaluation. This empowers individuals to actively participate in their reproductive healthcare with a clearer understanding of potential outcomes.